Urinary tract infections are a common social problem that affects both children and adults, and due to their anatomical structure, women are much more likely than men to experience unpleasant conditions. Often patients first seek help in a pharmacy.
The etiology of urinary tract infections
The most common cause of urinary tract infections are bacteria, and much less often fungi, viruses and parasites. They arrive by the following routes: ascending, that is to say by the urethra, hematogenous, lymphatic and by continuity. The first of them is the most important. The first stage usually involves the colonization of the urethral opening (in women – the vaginal area, in men – the subprepuce area) with bacteria from the patient’s own flora, which mainly comes from the gastrointestinal tract. Subsequently, the urethra invades the bladder. Due to the proximity of the vaginal opening, the urethra (also because it is shorter than in men) and the rectum, the risk of ascending infection is higher in women. Bacteria present in the bladder can reach the kidney through the ureters. Ascending infections are caused primarily by gram-negative intestinal bacilli, the most dominant of which is Escherichia coli. In turn, they respond to recurrent infections protea spp. Klebsiella spp. Gram-negative rods of the genera: Klebsiella, Enterobacter, Serratia, Pseudomonas and Gram-positive cocci: Staphylococcus epidermidis and Enterococcus foecalis they most often generate hospital urinary tract infections, which is linked to their resistance to antibiotics. Staphylococcus saprophyticus it causes urinary tract infections in sexually active young women  .
Risk of urinary tract infection
Women are much more prone to urinary tract infections than men, which is mainly due to their anatomical structure. A shorter urethra is important, as it remains more exposed to invasion from pathogens inhabiting the anus and vagina. Another problem is the tendency of women to incomplete emptying of the bladder during urination. The risk of infection also includes sexual intercourse, where pathogens can easily migrate from the urethra to the bladder.
Among the people particularly at risk of urinary tract infections, we also distinguish:
- men with an enlarged prostate
- pregnant women
- diabetic patients  .
Treatment of urinary tract infections
Pharmacotherapy of urinary tract infections, due to the etiology of the disease, is essentially based on antibiotics. Often, auxiliary drugs of plant origin are added, rich in many active compounds with bactericidal and bacteriostatic properties, modulating the motility of the urinary system and the composition and pH of urine, as well as increasing diuresis. Herbal preparations are a perfect complement to antibiotic therapy and chemotherapy (e.g. furazidine) and protect against recurrence of infection in accordance with prophylaxis .
Urosept – a herbal preparation recommended in urinary tract infections
Urosept is a herbal drug with a mild diuretic effect applied auxiliary in urinary tract infections and urolithiasis. The composition of the product is based on a composition of selected natural ingredients. It contains thick extracts of birch leaves, parsley root and bean, rich in flavonoids with strong diuretic properties. In addition, Urosept contains chamomile dry extract, which due to the abundance of active compounds has a soothing, anti-inflammatory and diastolic effect. A valuable component of the preparation is also lingonberry leaf extract, which has both diuretic and disinfectant properties in the urinary tract, which supports the treatment of nephrolithiasis and reduces the development of inflammation in the kidneys . Urosept, meeting the individual needs of the patient, depending on the duration of treatment, is available in packs of 30 and 60 pieces – Urosept 30 and Urosept 60 . The product is dedicated children above 12 years and adults – women and men struggling with the problem of urinary tract infections and kidney stones. Urospet, due to its diuretic, antibacterial, disinfectant and diastolic effects, is used as an auxiliary in the treatment of urinary tract infections, which more often affect the female sex. In men who are more likely to develop kidney stones than women, the drug helps break down kidney stones and helps prevent them from forming. It is recommended to dose Urosept 2 tablets 3 times a day with a glass of water or according to individual medical recommendations. Under the supervision of a specialist, the preparation can be used for a longer period, also in combination with other drugs    .
Farm MSc. Ilona Gołąbek – Karaś
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- Duława J. and Holecki M. Urinary tract infections in diabetic patients. Via Medica. 2009; ISSN 1734-3321: 36-39.
- https://pulsmedycyny.pl/leki-roslinne-w-infekcji-ukladu-moczowego-879941. [Online]
- https://www.herbapol.poznan.pl/pl/produkty/urosept-30. [Online]
- https://www.herbapol.poznan.pl/pl/produkty/urosept. [Online]
- CPS Urosept.
- Kohlmünzer S. Pharmacognosy. Warsaw: PZWL, 1997.
Urosept coated tablets. Active substances: 1 coated tablet contains: thick extract composed of birch leaves, parsley root, bean (Extractum spissum compositum (4-7:1) ex: Betulae folio 4.40 pieces, Radice Petroselini 2.66 parts, Phaseoli pericarp 1.00 parts, extractant: 90% methanol [v/v]) – 86.2 mg; bean powder (Phaseoli pericarp) – 78mg; dry extract from lingonberry leaves (Vitis idaeae leaf dry extract (3-6:1), extractant: water) – 26 mg; chamomile herb dry extract (Chamomillae herbae extractum siccum (7-9:1), extractant: water) – 8 mg; Potassium citrate (Kalii citras) – 19mg; sodium citrate (Natrii citras) – 16mg. Excipients with known effect: lactose, sucrose. Intended use: Urosept is a mild diuretic. It is used as an aid in urinary tract infections and urolithiasis. Dosage and method of administration: Adults and children over 12 years old: take 2 tablets orally 3 times a day, washed down with a glass of water or as individual doctor recommends. There are no data confirming the safety of use in children under 12 years of age. The medicine can be taken over a longer period under the supervision of a doctor, also in combination with other medicines. Contraindications: Hypersensitivity to active substances, plants of the Asteraceae family (AsteraceaePreviously Composed) or to one of the excipients. Special warnings and precautions for use: Do not use in the presence of edema caused by heart and kidney failure. It is not recommended for use in children under 12 due to lack of safety data. If symptoms worsen while taking the medicine, contact your doctor. Due to the presence of parsley root extract with potential photosensitizing properties, skin damage is unlikely to occur in fair-skinned people exposed to excessive sunlight. The medicine contains lactose monohydrate. The drug should not be used in patients with rare hereditary problems of galactose intolerance, lactase deficiency or glucose-galactose malabsorption. The medicine contains sucrose. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine. This medicinal product contains less than 1 mmol sodium (23 mg) per dose, that is to say essentially ‘sodium free’. Side effects: Due to the presence of parsley root extract with potential photosensitizing properties, skin damage is unlikely to occur in fair-skinned people exposed to excessive sunlight. So far, no side effects have been reported. Responsible entity: Poznańskie Zakłady Zielarskie Herbapol SA in Poznań. Marketing Permission: N°R/0801 issued by the URPLWMiPB. The drug is available without a prescription.